منابع مشابه
Genetic Control of Yeast Mannan Structure
Four Saccharomyces cerevisiae mannan mutants have been analyzed to assess the effect of the mutations on the properties of the cells and to determine the complementation patterns. The mutants were defective in the formation of an a-1+3-mannosyltransferase (mnnl), two different a-1+2mannosyltransferases (mnn2 and mnn3), and a mannosylphosphate transferase (mnnl). The latter mutant was obtained f...
متن کاملGenetic control of yeast mannan structure. Isolation and characterization of mannan mutants.
The yeast Saccharomyces cerevisiae X2180, the strain most commonly used for genetic studies on yeasts, was treated with the mutagen ethyl methanesulfonate, and mutants defective in the synthesis of cell wall mannan were isolated. The initial selection of mutants was made on the basis of their failure to agglutinate with antiserum that was specific for the mannotetraose side chain of the mannan,...
متن کاملGenetic control of yeast mannan structure: mapping genes mnn2 and mnn4 in Saccharomyces cerevisiae.
Two mutations concerned with mannan biosynthesis in the yeast Saccharomyces cerevisiae have been mapping. The mnn2 mutation, which affects the addition to the polysaccharide backbone of the first side-chain D-mannose unit in alpha1-leads to2 linkage, was located on chromosome II linked to the centromere and the gall locus. The mn4 locus, which regulates the synthesis of mannosylphosphate groups...
متن کاملStudies on the structure of yeast mannan. II. Mode of action of the Arthrobacter alpha-mannosidase on yeast mannan.
The mode of action of the extracellular a-mannosidase from Arfhrobacfer GJM-1 has been studied with several yeast mannans as substrates. In vifro, the enzyme cleaves most of the cu-(1 + 2)and a-(1 + 3)-linked side chains from Saccharomyces cerevisine mannan, producing free mannose and leaving a resistant polymer containing mainly ar-(1 --f 6)-linkages. This material cannot be further degraded b...
متن کاملImmunochemistry of pathogenic yeast, Candida species, focusing on mannan
This review describes recent findings based on structural and immunochemical analyses of the cell wall mannan of Candida albicans, and other medically important Candida species. Mannan has been shown to consist of α-1,2-, α-1,3-, α-1,6-, and β-1,2-linked mannopyranose units with few phosphate groups. Each Candida species has a unique mannan structure biosynthesized by sequential collaboration b...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1973
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)43713-7